Glutathione
Pre-Order10 mg · Lyophilized powder
Available for pre-order
L-Glutathione (γ-Glu-Cys-Gly) tripeptide.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. For laboratory research use only. Not for human or animal consumption.
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Quick Summary
Established biology — supplementation evidence limitedGlutathione is a three-amino-acid molecule (glutamate, cysteine and glycine) that cells make themselves. It is the main small antioxidant inside cells and helps neutralize reactive molecules and foreign chemicals. Its role in cells is well established; the effects of supplemented glutathione in people are uncertain.
Areas of research
- Oxidative stress and redox signaling
- Glutathione synthesis and regulation
- Xenobiotic detoxification
- Oral supplementation and body stores
- Immune function
- Amount
- 10 mg
- Form
- Lyophilized powder
- References
- 4 cited
- COA
- Batch report pending
- Free U.S. shipping over $150
- Lyophilized powder in a sealed vial
Research Use Notice. This product is intended for laboratory and research purposes. It is not intended for human consumption or personal medical use. Product information is provided for scientific and educational context only. See our Research Use Policy.
Why Researchers Study It
- The main antioxidant defense inside cells
- Redox signaling and oxidative stress
- Detoxification of foreign chemicals
- Whether supplemented glutathione raises the body's own stores
What It IsGlutathione is a tripeptide made of glutamate, cysteine and glycine, linked through an unusual γ-glutamyl bond (γ-Glu-Cys-Gly).
Glutathione is a tripeptide made of glutamate, cysteine and glycine, linked through an unusual γ-glutamyl bond (γ-Glu-Cys-Gly). Cells make it themselves, and in cells it exists mostly (over 98%) in its reduced form, often abbreviated GSH.
It is made in two energy-requiring steps by the enzymes glutamate-cysteine ligase and glutathione synthetase.
Glutathione is the main small-molecule antioxidant inside cells, so it is central to research on oxidative stress, redox signaling and the detoxification of foreign chemicals. It also has roles in cell growth, cell death and immune function.
A separate research question is whether glutathione given from outside the body raises the body's own stores. Controlled trials of oral glutathione have produced mixed results.
How It Works3 established · 2 proposed or under investigation
Established
- Acts as the predominant cellular antioxidant against oxidative stress
- Synthesis is limited by glutamate-cysteine ligase and regulated by transcription factors including Nrf2
- Participates in detoxifying foreign compounds (xenobiotics)
Proposed / under investigation
- Whether oral or other supplemental glutathione meaningfully raises tissue levels in people
- Downstream effects of supplementation on immune markers, such as natural killer cell activity
Research Status & EvidenceEstablished biology — supplementation evidence limited
Glutathione's role inside cells is established by decades of biochemistry; small human supplementation trials have given mixed results.
Types of evidence
- Available: Cell & lab studies
- Not available: Animal studies
- Available: Early human studies
- Not available: Clinical trials
- Not available: Approved medical use
Glutathione's role inside cells is well established by decades of biochemistry. Evidence on supplemented glutathione is limited and mixed: a 6-month trial in 54 adults reported higher glutathione in blood cells, while a 4-week trial in 40 adults found no change in glutathione status or oxidative-stress markers.
Areas of research
- Oxidative stress and redox signalingcore cell biology
- Glutathione synthesis and regulationenzymes and Nrf2 signaling
- Xenobiotic detoxificationcellular defense against foreign chemicals
- Oral supplementation and body storessmall randomized trials
- Immune functionimmune-cell markers in supplementation studies
Limitations
- Its biological role inside cells is established; the effects of supplemented or administered glutathione are not
- Human supplementation trials are small, short and inconsistent
- No FDA-approved glutathione drug product was identified; it is a nominated compounding substance under FDA evaluation
Specifications10 mg · Lyophilized powder · CAS 70-18-8
- Product
- Glutathione
- Category
- Research Compounds
- Size
- 10 mg
- Form
- Lyophilized powder
- Synonyms
- L-Glutathione; GSH; Reduced glutathione; γ-L-glutamyl-L-cysteinylglycine
- CAS number
- 70-18-8
- Molecular formula
- C10H17N3O6S
- Molecular weight
- 307.33 g/mol
- Sequence
- γ-Glu-Cys-Gly (γ-L-glutamyl-L-cysteinylglycine)
- PubChem CID
- 124886
- SKU
- REN-GLUT-10
Molecular data: Reduced glutathione, GSH (PubChem).
Testing & COA Batch report pending
Research References (4)Linked sources · last reviewed September 2026
- Lu SC. Glutathione synthesis. Biochim Biophys Acta 2013 · PubMed 22995213
- Richie et al. Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. Eur J Nutr 2015 · link.springer.com
- Allen & Bradley. Effects of oral glutathione supplementation on systemic oxidative stress biomarkers in human volunteers. J Altern Complement Med 2011 · PubMed 21875351
- FDA. Bulk Drug Substances Nominated for Use in Compounding Under Section 503A (updated May 14, 2026) · fda.gov
Summaries are written by Renuvia Labs from the sources above for educational context only. Last reviewed September 28, 2026.
Frequently Asked Questions
What form is this product supplied in?
Peptides and research compounds ship as lyophilized (freeze-dried) powder in a sealed glass vial. The fill amount printed on the product page and label is the total content of the vial.
Is this product for human use?
No. All Renuvia Labs products are sold strictly for laboratory research use. They are not for human or animal consumption and are not intended to diagnose, treat, cure or prevent any disease.
Where can I find the Certificate of Analysis?
When a batch has a Certificate of Analysis, it is linked in the Testing & COA section of the product page and listed in the COA library, searchable by product, SKU or batch number.
Do you offer volume pricing?
Yes. Per-vial pricing drops automatically at 2, 3 and 5 vials of the same product; the current tiers are shown next to the price. For larger quantities, see our wholesale program.
How much is shipping?
U.S. orders of $150 or more ship free. Orders below that ship at a flat rate, shown in the cart.
