Klow
In stock80 mg · Lyophilized powder
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Four-peptide research blend: GHK-Cu, BPC-157, TB-500 and KPV.
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For laboratory research use only by qualified researchers. Not for human or veterinary use. Not a drug, dietary supplement, cosmetic or food. Not evaluated by the FDA for any use.
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Quick Summary
Preclinical — blend not studiedKlow is a commercial four-peptide blend of GHK-Cu, BPC-157, TB-500 and KPV in one vial. Each ingredient has its own research history, mostly in skin, inflammation and tissue-repair models. The blend itself has no published research, and none of the ingredients is an approved drug.
Areas of research
- Skin and collagen biology
- Wound healing
- Intestinal inflammation
- Musculoskeletal repair
- Gene-expression profiling
- Amount
- 80 mg
- Form
- Lyophilized powder
- References
- 6 cited
- COA
- Published
- Free U.S. shipping on orders of $150 or more
- Lyophilized powder in a sealed vial
- Batch COA available
Research Use Notice. This product is intended for laboratory and research purposes. It is not intended for human consumption or personal medical use. Product information is provided for scientific and educational context only. See our Research Use Policy.
Why Researchers Study It
- GHK-Cu, a copper-binding peptide found in human plasma, has a long record in skin and wound research
- KPV has been studied for inflammatory signaling in intestinal cells and mouse colitis models
- BPC-157 and TB-500 appear mainly in animal tissue-repair studies
- Their shared research themes, inflammation and tissue repair, are why the four are grouped together
What It Is
Klow is a trade name for a four-peptide mixture: GHK-Cu, BPC-157, TB-500 and KPV in a single vial.
Klow is a trade name for a four-peptide mixture: GHK-Cu, BPC-157, TB-500 and KPV in a single vial. It is a commercial blend, not a compound with its own scientific literature.
GHK-Cu is a copper-bound tripeptide (glycyl-histidyl-lysine) found naturally in human plasma. KPV is the tripeptide Lys-Pro-Val, the last three amino acids (11–13) of α-melanocyte-stimulating hormone. BPC-157 is a 15-amino-acid gastric-derived peptide, and TB-500 is an acetylated 17–23 fragment of thymosin β4.
Each ingredient has been studied on its own. GHK-Cu has a long record in skin and wound research and is used in topical cosmetic products. KPV has been studied for anti-inflammatory effects in intestinal cells and mouse colitis models. BPC-157 and TB-500 appear mainly in animal tissue-repair studies.
The shared research themes, inflammation and tissue repair, explain why the four are marketed together. No peer-reviewed study of the four-way blend was identified.
How It Works
3 established · 4 proposed or under investigation
Established
- GHK-Cu is a copper complex of the tripeptide GHK that occurs naturally in human plasma
- In cell and mouse experiments, KPV is carried into intestinal cells by the peptide transporter PepT1
- No mechanism has been established for the four-peptide blend
Proposed / under investigation
- GHK-Cu: proposed to stimulate collagen and elastin production and to shift expression of many repair-related genes
- KPV: shown in cell and mouse models to dampen NF-κB and MAP-kinase inflammatory signaling
- BPC-157: rodent work links it to blood-vessel growth pathways and lower inflammatory cytokines
- TB-500: whether this fragment reproduces effects of full-length thymosin β4 remains unclear
Research Status & Evidence
Preclinical — blend not studied
The evidence belongs to the individual ingredients: mostly cell and animal studies, plus small human studies of topical GHK-Cu cosmetics.
Types of evidence
- Available: Cell & lab studies
- Available: Animal studies
- Available: Early human studies
- Not available: Clinical trials
- Not available: Approved medical use
The evidence belongs to the individual ingredients, not the blend. It is mostly cell and animal work, plus small human studies of topical GHK-Cu cosmetics and a single BPC-157 case series. FDA has noted no human exposure data for KPV or the TB-500 fragment by any route.
Areas of research
- Skin and collagen biologyGHK-Cu, including topical cosmetic studies
- Wound healingGHK-Cu in animal and cell models
- Intestinal inflammationKPV in mouse colitis models
- Musculoskeletal repairBPC-157 and TB-500 in rodents
- Gene-expression profilingGHK-Cu transcriptional data
Limitations
- No published research has studied this four-peptide blend or its specific ratios
- None of the four ingredients is an FDA-approved drug
- Human data on GHK-Cu relate mainly to topical cosmetic products
- BPC-157 and TB-500 are prohibited in sport under the WADA 2026 list
Specifications
80 mg · Lyophilized powder
- Product
- Klow
- Category
- Blends
- Size
- 80 mg
- Form
- Lyophilized powder
- Synonyms
- GHK-Cu / BPC-157 / TB-500 / KPV blend
- SKU
- REN-KLOW-80
Testing & COA Batch report available
- Batch RN-2610-KLOW · HPLC-UV (purity), LC-MS (identity) · Freedom Diagnostics Testing · 2026-10-3199.69% purity · Identity: confirmed · GHK-Cu 53.82 mg, BPC-157 10.81 mg, TB-500 10.05 mg, KPV 10.27 mg measured (84.95 mg total; 80 mg on label). The lab report lists the sample as the "Clear Cap" vialView COA
Research References (6)
Linked sources · last reviewed September 2026
- Pickart & Margolina. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci 2018 · PubMed 29986520
- Dalmasso et al. PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation. Gastroenterology 2008 · PubMed 18061177
- Vasireddi et al. Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review. HSS J 2025 · PubMed 40756949
- Esposito et al. Synthesis and characterization of the N-terminal acetylated 17-23 fragment of thymosin beta 4 identified in TB-500. Drug Test Anal 2012 · PubMed 22962027
- Biçer et al. Effects of BPC-157 and TB-500 on Achilles tendon healing in rats. Jt Dis Relat Surg 2026 · PubMed 42542926
- FDA. Certain bulk drug substances for use in compounding that may present significant safety risks (updated Apr 2026) · fda.gov
Summaries are written by Renuvia Labs from the sources above for educational context only. Last reviewed September 28, 2026.
Frequently Asked Questions
What is in Klow?
Klow is a four-peptide blend of GHK-Cu, BPC-157, TB-500 and KPV, supplied as one lyophilized vial with 80 mg total content. The amount of each component will be listed with the lot's Certificate of Analysis.
How much does Klow cost?
$119.99 per 80 mg vial, with per-vial pricing that drops automatically at 2, 3 and 5 vials (the current tiers are shown next to the price). Nothing is charged at reservation; free U.S. shipping applies on orders of $150 or more.
Is Klow sold by Renuvia Labs third-party tested?
Every Klow lot is assigned a lot number and listed in the COA library, where its Certificate of Analysis is published when the laboratory issues it. Until then the lot shows as pending and no purity figure is quoted.
What is Klow?
Klow is a commercial four-peptide blend of GHK-Cu, BPC-157, TB-500 and KPV in one vial. Each ingredient has its own research history, mostly in skin, inflammation and tissue-repair models. The blend itself has no published research, and none of the ingredients is an approved drug.
Is there a Klow coupon or discount code?
There is no public coupon code. New customers get a first-order discount for joining the Renuvia email list, volume pricing starts at 2 vials of Klow, and U.S. shipping is free over $150. Codes on third-party coupon sites are not valid here.
What are other names for Klow?
Klow is also referred to as GHK-Cu / BPC-157 / TB-500 / KPV blend.
What sizes is Renuvia Labs Klow available in?
Klow is listed in 80 mg, supplied as lyophilized powder in a sealed glass vial. It is sold for laboratory research use only.
Where is the Certificate of Analysis for Klow?
Certificates of Analysis are published per lot in the Renuvia Labs COA library, searchable by product, SKU or lot number. Klow shows "pending" there until the current lot's report exists; it is then linked on this page too.
Is this in stock?
Yes, unless the page says sold out. You reserve it with no payment today, and we email payment instructions in approximately 1–2 business days. Your order ships once payment arrives.
What form is this product supplied in?
Peptides and research compounds ship as lyophilized (freeze-dried) powder in a sealed glass vial. The fill amount printed on the product page and label is the total content of the vial.
Is this product for human use?
No. All Renuvia Labs products are sold strictly for laboratory research use. They are not for human or animal consumption and are not intended to diagnose, treat, cure or prevent any disease.
Do you offer volume pricing?
Yes. Per-vial pricing drops automatically at 2, 3 and 5 vials of the same product; the current tiers are shown next to the price. For larger quantities, see our wholesale program.
How much is shipping?
Free U.S. shipping on orders of $150 or more; $8.95 flat rate below that.
Do you ship outside the U.S.?
No. Renuvia Labs ships to U.S. addresses only. Research institutions outside the U.S. can enquire through the wholesale program.
