Selank
Pre-Order11 mg · Lyophilized powder
Available for pre-order
Synthetic heptapeptide analog of tuftsin.
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Quick Summary
Early clinical research (Russia) — not FDA-approvedSelank is a synthetic seven-amino-acid peptide built from tuftsin, a small immune-related peptide, with a tail added for stability. It has been studied, mainly in Russia, in animal models of anxiety-related behavior and for its effects on genes linked to the GABA neurotransmitter system. Human studies are small, and it is not FDA-approved.
Areas of research
- Anxiety-related behavior
- GABAergic neurotransmission
- Neuroimmune signaling
- Small clinical comparisons
- Amount
- 11 mg
- Form
- Lyophilized powder
- References
- 3 cited
- COA
- Batch report pending
- Free U.S. shipping over $150
- Lyophilized powder in a sealed vial
Research Use Notice. This product is intended for laboratory and research purposes. It is not intended for human consumption or personal medical use. Product information is provided for scientific and educational context only. See our Research Use Policy.
Why Researchers Study It
- Anxiety-related behavior in rodent models
- Brain gene expression linked to GABA signaling
- Immune signaling inherited from its parent peptide, tuftsin
- Small clinical comparisons in Russian studies
What It IsSelank is a synthetic peptide of seven amino acids (Thr-Lys-Pro-Arg-Pro-Gly-Pro).
Selank is a synthetic peptide of seven amino acids (Thr-Lys-Pro-Arg-Pro-Gly-Pro). It was built from tuftsin, a small immune-related peptide, extended with a Pro-Gly-Pro tail that makes it more stable.
It was developed and studied mainly by Russian research institutes. It is not approved by the FDA.
Selank is of research interest because rodent studies suggest it changes anxiety-related behavior while also affecting immune signaling, a combination inherited from its tuftsin origin.
Researchers have also examined how it changes gene expression in the brain, including genes linked to the GABA neurotransmitter system.
How It Works0 established · 2 proposed or under investigation
Established
No mechanism of action has been firmly established for Selank.
Proposed / under investigation
- Allosteric modulation of GABAergic signaling, suggested by gene-expression changes in rat frontal cortex
- Immunomodulatory effects related to its parent peptide, tuftsin
Research Status & EvidenceEarly clinical research (Russia) — not FDA-approved
Mostly animal work plus small human studies published mainly in Russian journals, with little independent replication.
Types of evidence
- Not available: Cell & lab studies
- Available: Animal studies
- Available: Early human studies
- Not available: Clinical trials
- Not available: Approved medical use
Most evidence comes from animal work by a small number of Russian groups. Human data are limited to small studies published mainly in Russian journals, such as a 62-patient comparison with the drug medazepam, with little independent replication.
Areas of research
- Anxiety-related behaviorrodent models
- GABAergic neurotransmissiongene-expression studies in rats
- Neuroimmune signalingtuftsin-derived activity
- Small clinical comparisonsRussian studies
Limitations
- Not approved by the FDA or the European Medicines Agency
- Human studies are small and mostly from the developers' institutions
- FDA has cited a potential immunogenicity risk related to aggregation and peptide impurities
Specifications11 mg · Lyophilized powder
- Product
- Selank
- Category
- Peptides
- Size
- 11 mg
- Form
- Lyophilized powder
- Synonyms
- Thr-Lys-Pro-Arg-Pro-Gly-Pro; TKPRPGP
- Sequence
- Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP)
- SKU
- REN-SELK-11
Molecular data: Sequence per FDA Global Substance Registration System.
Testing & COA Batch report pending
Research References (3)Linked sources · last reviewed September 2026
- Volkova A et al. Selank administration affects the expression of some genes involved in GABAergic neurotransmission. Front Pharmacol 2016 · frontiersin.org
- Zozulia AA et al. Efficacy and possible mechanisms of action of a new peptide anxiolytic Selank in the therapy of generalized anxiety disorders and neurasthenia. Zh Nevrol Psikhiatr 2008 · PubMed 18454096
- FDA. Certain bulk drug substances for use in compounding that may present significant safety risks (updated April 2026) · fda.gov
Summaries are written by Renuvia Labs from the sources above for educational context only. Last reviewed September 28, 2026.
Frequently Asked Questions
What form is this product supplied in?
Peptides and research compounds ship as lyophilized (freeze-dried) powder in a sealed glass vial. The fill amount printed on the product page and label is the total content of the vial.
Is this product for human use?
No. All Renuvia Labs products are sold strictly for laboratory research use. They are not for human or animal consumption and are not intended to diagnose, treat, cure or prevent any disease.
Where can I find the Certificate of Analysis?
When a batch has a Certificate of Analysis, it is linked in the Testing & COA section of the product page and listed in the COA library, searchable by product, SKU or batch number.
Do you offer volume pricing?
Yes. Per-vial pricing drops automatically at 2, 3 and 5 vials of the same product; the current tiers are shown next to the price. For larger quantities, see our wholesale program.
How much is shipping?
U.S. orders of $150 or more ship free. Orders below that ship at a flat rate, shown in the cart.
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